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    1. 63日上午4:54

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4期食管腺癌(EAC)的積極進展過程

親愛的朋友們!這是我丈夫癌症之旅的積極進展。

 我先與大家分享壞消息和得病經過。

傑里米於201812月被診斷為1-2EAC

 20191月:實施化學/質子輻射6

 食管切除術20193月:切除49個淋巴結,其中4個呈陽性。

 20194月實施了無穀物的榨汁和嚴格的素食飲食。

 201910月的CT掃描顯示有5次肝癌並經活檢證實。

 201911月開始Jane的療法,COC meds和靜脈注射高C

 20201月的CT掃描顯示5個腫瘤有少許縮小:開始使用60%含氧鉑的5 FU化療。

56日,傑里米進行了7輪化療後,進行了CT掃描以檢查進展情況。

 他還繼續服用COC藥物,補品,飲食。

 CT掃描顯示以前的肝腫瘤沒有變化,並且增加了3個較大的腫瘤:81x40mm28x35mm49x36mm

他的腫瘤醫師下令對肝臟進行MRI檢查,以獲得更好的觀察,並希望肝臟上的這些較大斑點可能是良性的。

所有CT掃描都非常準確,因此認為它是良性的。

儘管這令人傷心的消息,我們在這一切中都處於谷底,但也充滿了極大的盼望。

我們被打敗了,但仍將一切都託付給上帝。

來自主的眷顧是第一個奇蹟。

第二個奇蹟發生在一周後,肝臟MRI顯示沒有發現3個大斑點,剩下的只有3個豌豆大小的腫瘤!

我們非常感激。信任,信仰上帝,祂教訓已經徹底改變了生活。

我們的治療仍在繼續,我們已決定不再繼續進行化學治療。

 我們將繼續飲食,補品和吃COC藥物。

 上週我們通過電話與馬克·羅森伯格(Mark Rosenberg)舉行了一次會議,很可能會改變傑里米目前的治療方案。

現在我與您分享傑里米目前的治療方法。

我們希望您能夠從我們的治療過程中獲得一些有用的信息。

 

傑里米的療法:

早上例行:用過濾水,然後加胡蘿蔔,芹菜,檸檬,姜,薑黃,青蘋果,大蒜汁  打汁喝。

祈禱,聖經閱讀時間

吃早餐和食品補充劑。

使用4種護理腫瘤處方:

1.二甲雙胍Metformin 500mg每天3

功用-通過激活p53抑癌基因來降低腫瘤細胞的生長,增強化學反應,並抑制IGF-1GLN phosmTORF.A.S,胰島素和oxphos途徑

2.Atrovastin (降血脂) 40 mg每天1

 作用:阻止癌細胞產生新癌細胞的膽固醇的能力,凋亡(殺死癌症),增強化學作用,具有強力的NSAID增加殺死的癌症5倍,抑制Glut 1和甲羥戊酸的攝取途徑

3.甲苯咪唑Mebendazole 200毫克,每天1次,每次1次,服用1茶匙橄欖油混和黑胡椒粉用以增加吸收。

功用:減慢快速的細胞分裂,破壞癌細胞幹細胞,破壞癌細胞中的微血管形成,破壞腫瘤相關的巨噬細胞,凋亡,增強化學作用,抑制:MMP-2

多西環素Doxycycline每日100毫克,吃1個月停吃一個月,這可在小腸內吸收,因此有助於保存腸道細菌

作用:減少轉移擴散,殺死癌症幹細胞,抑制物:MMP-9glut ox phosF.A.S.Oxphos途徑

 *注意:與鐵,鋅等要分開食用,間格要2小時

 在靜脈注射高C後至少5個小時才使用多西環素,因為它會干擾ROS

其他處方:

1.雙嘧達莫Dipyridamole 50毫克每天一次。

功用:抗凝,減少代謝,在癌細胞中保持更長時間的化學作用,抑制:核苷拯救和SREP-2途徑,阻止生長因子:MMP-9PDGFTGFB

2.Celebrex 100mg每天一次

功用:COX 2抑製劑,與低劑量化療和IV維生素C結合顯著增加癌症殺傷力,打斷癌症DNA的複製,降低患胃潰瘍的風險。

3.低劑量納曲酮(LDN-治療與食道癌相關的異常細胞信號轉導(TLR-4)(於5/2020停用)使用低劑量(60%)的化療藥物 氟尿嘧啶(5-FU)和奧沙鉑每隔一周,靜脈緩慢輸注。

功用-破壞快速分裂的細胞,並結合其他處方/補充劑應具有更強的抗癌作用

補充品:

1.高劑量IV維生素C 75 mg注射,每週2-3

 功用:產生過氧化氫對癌細胞有選擇性的毒性。

 -這是注射抗氧化劑和Glut 1抑製劑,注射後5-8小時達到峰值。

2.魚油(3,600毫克/次)與歐米茄32,160毫克次)

 作用:有助於炎症,減少他汀類藥物的副作用。

3.D3每天15,000-20,000 IU

 功用-增強免疫系統,抑制mTORPPARγ途徑,減少他汀類藥物的副作用

4.硫酸葡萄糖胺Glucosamine sulphate每天1500毫克

 作用-益生元MMP-3的生長抑製劑,可減輕炎症

5.木犀草素與蘆丁Luteolin with Rutin每天100mg:這是抗氧化劑,有助於與頭/頸癌相關的異常細胞信號傳導(Notch)。 SREBP-2抑製劑。芹菜汁中富含木犀草素 -在殺癌階段停止-

每日小球藻Chlorella 1200毫克

 功效:排毒,植物營養素,抗氧化劑,益生菌,減少炎症

 *有助於ct掃描後排毒

6.1000億個原始益生菌Raw Probiotics,含34種菌株-每天1

7.服用Bifido Digest消化液生菌 200cfu-每天2

功用:保持腸道菌群健康

8.薑黃(薑黃素)Tumeric (curcuminoid)每天5,000-8,000mg +

作用:抑制腫瘤生長,炎症,增強化學作用,抑制血管生成,促進細胞凋亡,抑制:通過限制癌細胞的生存途徑來抑制谷氨酰胺分解途徑-Nf-KBEGFR

9.槲皮素Quercetin -每日1,300mg

 功用:阻斷Glut 1通路,EGFR和異常細胞信號轉導

10.熊果酸(聖羅勒)Ursolic acid (Holy Basil)-每天200毫克

 作用:保留肌肉質量,抑制谷氨酰胺分解途徑,增強化學作用

11.白藜蘆醇Resveratrol 75毫克每天

 作用:抗氧化,有助於他汀類藥物的副作用,抑制谷氨酰胺分解途徑和Nf-KB,增強化學作用,葡萄籽油有助於Fu-5的副作用

12.甲基維生素BMethyl B-Complex 50,每天2

 功用:有助於二甲雙胍的代謝以及許多其他必要的好處

13.黃連素Berberine每日1克(吃8週停吃4周)

 作用:降低重要的癌症巨胞飲的營養供應途徑,可在營養貧乏的腫瘤微環境中限制癌細胞的細胞生長,促進細胞凋亡,抗炎,抗真菌,抑制:Gln phosmTORSREBP-1ox phos和胰島素途徑,增強化療5-FU敏感性,尚可抑制MCF-7細胞的活力

14.氯雷他定(克拉瑞汀)Loratadine (Claritin)每天10mg

 作用:干擾癌細胞的自噬作用(強細胞吃掉弱細胞,讓癌腫瘤越來越堅強百毒不清侵),破壞癌細胞的溶酶體,降低代謝當量 ,增強化學反應,幫助注射引起的骨痛,刺激白血球的生成。

15.全天補充綠茶萃取物(EGCG1,000毫克與喝綠茶

 作用:誘導細胞凋亡,減少血管生成和谷氨酸,增強化學作用,抑制谷氨酰胺分解途徑

16.小白菊Feverfew 830mg

功用:降低穀胱甘肽(在殺傷階段保護癌症),產生活性氧(R.OS.),激活Capase 7-8-9

17.每天阿司匹林Aspirin 81毫克(目前不與Celebrex一起服用)

 作用:抗血小板,通過抑制VEGF生長因子來阻止血管生成,消炎,減少代謝,有助於阻止F.A.S. CSC代謝途徑

18.褪黑激素Melatonin 120mg/

 * 在實施CT掃描前吃300 mg 可以以減少輻射吸收量。

 作用:降低化學療法的毒性作用,同時增強作用,通過限制癌細胞進入血液來抑制癌症,增加T細胞,抑制血管生成。

19.檸檬酸與藤黃果Hydroxycitrate with garcinia cambogia每天750 mg

作用:模仿禁食,增強化學作用,抑制ACLY脂肪酸途徑

20.水飛薊Milk thistle 1000mg/

 功用:幫助肝臟排毒,有助於黃連素發揮功效,並可增強化療作用

21. 達胃新Tagamet 200mg每天

 功用-減少代謝,增加血液中甲苯達唑的含量,減少炎症,減少胃潰瘍,減少愛潑斯坦棒狀病毒和術後發炎。

23.每天菸酸Niacin 500mg

 功用-改善血液循環

24. S-腺苷甲硫氨酸SAM-E 400毫克

 功用:促進肝臟健康,請參考發表關於乳腺癌/肝癌的醫學文章

25.乳香Boswellia每天1

26每天古巴香脂Copaiba 120mg

 功用:肝臟健康和炎症

27.鯊魚肝油-每天2

 功用:提高白血球數量。

28.黑籽油Black seed oil 1茶匙

 功用:增加T細胞

29. 舞茸灰樹花Maitake-D-fraction 18.3毫克 在晚上服用 以及

5種免疫力增強食品”-火雞尾,靈芝,舞茸,香菇和查加菌核turkey tail, Reishi, Maitake, Shiitake, and chaga sclerotia -每天2

 功用:增強免疫系統,增加自然殺傷(NK)細胞,MMP-2

30.Beta葡聚醣Beta Glucan 250mg在晚上服用

 功用:有助於消除化學物質的免疫消耗,增加NK細胞

31. 匙羹藤Gymneman Slyvestre夜間服用600毫克

 功效:抗氧化,抗細菌,支持健康的血糖,增加NK細胞,有助於化學物質的免疫消耗

32. 普羅坎大麻二酚Procana CBD Ultra by Procana-打化學日當天100mg  幫助噁心和炎症

其他支持生命療法:

1.遠紅外線桑拿Far Infrared sauna 功效:促進身體排毒

2.瀉鹽/小蘇打/精油浴

 功效:促進癒合,減少炎症和排毒

3.與妻子步行:一周中幾乎每天走2-4英里

 作用:增加組織的氧合作用,促進力量和頭腦清晰

4.防止發炎秘訣-低糖食物,不吃穀物,無乳製品,主要是素食(偶爾捕撈野生魚類)

5.大部分時間下午小睡(30-45分鐘)

6.Berkey過濾水,偶爾添加臭氧,促進胃腸道組織癒合

 

以下是原文:

Positive progress: Stage 4 esophageal adenocarinoma (EAC)

 

Hi dear friends! This is a positive progress update on my husband’s cancer journey.

 Hang in there with me as I share the bad news first along with background information.

 

Jeremy was diagnosed with stage 1-2 EAC December 2018.

 Jan. 2019: Chemo/proton radiation 6 weeks

 Esophagectomy March 2019: 49 lymph nodes removed, 4 positive for cancer.

 April 2019 implemented juicing and strict vegan diet with no grains.

 October 2019 CT scan showed 5 liver 代謝當量  and was confirmed with biopsy.

 November 2019 started Jane’s protocol, COC meds, and IVC.

 January 2020 CT scan showed 5 tumors and a little shrinkage: 60% 5 FU with oxyplatin started.

May 6th Jeremy had CT scan done to check progress after 7 rounds of chemo.

 He has also continued COC meds, supplements, diet.

 CT scan showed no change to previous liver tumors AND an addition of 3 MUCH larger tumors: 81x40mm, 28x35mm, 49x36mm.

His oncologist ordered an MRI of liver to get better look with hopes that perhaps these larger spots on liver were something benign.

 I was not wasting emotional energy thinking it was benign as all other ct scans have been very accurate.

 We were at the end of ourselves with it all but also filled with a great peace despite the heart breaking news.

 We were shattered yet still trusting God with it all.

The peace from the Lord and surrender was the first miracle.

 The second miracle came a week later the MRI of liver showed the 3 large spots were no where to be found and all that remained were 3 pea sized tumors!

We are beyond thankful.

 The lessons in trust, faith, and walking with God have been completely life changing..even in the bleak valleys.

Our journey continues and we’ve made the decision not to continue chemo.

 We have a peace about continuing with diet, supplements, and COC meds.

 We had a meeting on the phone with Dr.Mark Rosenberg last week and will most likely add and make changes to Jeremy’s current regimen.

I will share with you Jeremy’s current regimen.

 Our paths may look very different but it is our hope that you’re able to glean some helpful things from our journey.

We love you all & pray for your healing AND most of all you would have the peace that surpasses understanding no matter your circumstances

(We have a private family/friends group on Facebook “Jeremy’s Health updates” if you wish to join, feel free. It also is where I give updates of Jeremy’s mom who was diagnosed with stage 4 lung cancer a few short months after Jeremy’s diagnosis)

Jeremy’s protocol:

Morning routine: Hydrating with filtered water followed by carrot, celery, lemon, ginger, tumeric, green apple, garlic juice

 & prayer, bible reading time

Breakfast & taking of mass prescriptions/supplements

4 Care Oncology prescriptions:

 Metformin 500mg 3 x a day

 Action- Reduces tumor cell growth & 代謝當量  by activating p53 tumor supressing gene, enhances chemo, inhibits: IGF-1, GLN phos, mTOR, F.A.S., insulin, and oxphos pathways

Atrovastin 40 mg 1 x a day

 Action: blocks cancer cells ability to make cholesterol for new cancer cells, apoptosis (cancer kill), enhances chemo, with strong NSAID increases cancer kill x 5, inhibits Glut 1 & mevolonate feeding pathways

Mebendazole 200mg 1 x a day, 1 month on 1 off, take with 1TBS of olive oil and black pepper to increase absorption

 Action: slows down fast cell division, destroys cancer stem cells, disrupts microtubule formation in cancer cells, destroys tumor associated macrophage cells, apoptosis, enhances chemo, inhibits: MMP-2

Doxycycline 100mg daily, 1 month on 1 off, absorbed in small intestine so helps preserve gut bacteria

 Action: decrease metastatic spread, kill of cancer stem cells, Inhibits: MMP-9, glut ox phos, F.A.S., & Oxphos pathways

 *take 2hrs apart from iron, zinc, etc

 No doxy until at least 5 hrs after IVC because it interferes with ROS

Other prescriptions:

Dipyridamole 50 mg daily

 Action: Anti- coagulant, decrease 代謝當量 , holds chemo in cancer cells longer, inhibits: nucleoside salvage & SREP-2 pathways, blocks growth factors: MMP-9, PDGF, TGFB

Celebrex 100mg daily

 Action: COX 2 inhibitor, increases cancer kill significantly combined with low dose chemo & IV vit C, disrupts “s” phase of cancer DNA replication, decreases risk of stomach ulcers

Low Dose Naltrexone (LDN)- treats abnormal cell signaling (TLR-4) associated with esophageal cancer

(Discontinued 5/2020) Lower dose (60%) chemo with

 Fluorouracil (5-FU) and Oxaplatin every other week slow infusion

 Action- destroys rapidly dividing cells and with combination of other prescriptions/supplements should have stronger effect against cancer

Supplements:

High dose IV Vitamin C 75mg, 2-3 x a week

 Action: selectively toxic to cancer cells by producing hydrogen peroxide

 - IVC days no anti-oxidants and Glut 1 inhibitors until most of IVC is peaked- 5-8hrs

Fish oil (3,600mg) with Omega 3 (2,160mg)

 Action: helps with inflammation, decreases side effects of statin

D3 15,000-20,000 IU daily

 Action- enhances immune system, inhibits mTOR & PPAR gamma pathways, decreases side effects of statin

Glucosamine sulphate 1500 mg daily

 Action- MMP-3 growth inhibitor, pre-biotic, reduces inflammation

Luteolin with Rutin 100mg daily- antioxidant, helps with abnormal cell signaling (Notch) associated with head/neck cancers. SREBP- 2 inhibitor. Celery juice also high in Luteolin

 -Stop during kill phase-

 (Page 311)

Chlorella 1,200 mg a daily

 Action: detox, phytonutrients, antioxidant, pro-biotic, decrease inflammation

 * helps detox after ct scan

Raw Probiotics 100 billion with 34strains- 1 x daily

Bifido Digest 20 billion cfu- 2 daily

 Action: keeps gut flora healthy

Tumeric (curcuminoid) 5,000-8,000mg+ daily

 Action: inhibits tumor growth, inflammation, enhances chemo, inhibits angiogenesis, promotes apoptosis, inhibits: glutaminolysis pathway by restricting cancer cell survival pathways- Nf-KB, EGFR

Quercetin- 1,300mg daily

 Action: blocks Glut 1 pathway, EGFR, and abnormal cell signaling

Ursolic acid (Holy Basil)- 200 mg daily

 Action: preserves muscle mass, inhibits glutaminolysis pathway, enhances chemo

Resveratrol 75 mg daily

 Action: anti-ox, helps with side effects of statin, inhibits glutaminolysis pathway & Nf-KB, enhances chemo, grape seed oil helps with side effects of Fu-5

Methyl B-Complex 50, 2 daily

 Action: helps with metformin depletion along with many other necessary benefits

Berberine 1 gram daily (8 weeks on 4 weeks off)

 Action: decrease cancer 代謝當量 , promotes apoptosis, anti- inflammatory, anti- fungal, inhibits: Gln phos, mTOR, SREBP-1, ox phos, and insulin pathways, combined with 5-FU inhibits viability of MCF-7 cells

Loratadine (Claritin) 10mg daily

 Action: interferes with micropinocytosis of cancer cells, destruction of cancer lysosomes, decrease 代謝當量 , enhances chemo, helps with bone ache from injection (Neupogen?) to stimulate WBCs

Green tea (EGCG) supplement 1,000 mg & tea throughout the day

 Action: induces apoptosis, decreases angiogenesis and glutamate, enhances chemo, inhibits glutaminolysis pathway

Feverfew 830mg daily

 Action: lowers glutathione (protects cancer during kill phase), generates reactive oxygen species (R.OS.), activates capase 7, -8, -9

Aspirin 81 mg daily (not taking currently with Celebrex)

 Action: anti-platlet, blocks angiogenesis through VEGF growth factor inhibition, anti-inflammatory, decreases 代謝當量 , helps block F.A.S. & CSC metabolic pathway

Melatonin 120mg at night

 * 300mg pre- ct scan to decrease amount of radiation absorbed

 Action: reduces toxic effects of chemo while enhancing effects, inhibits cancer 代謝當量  by limiting entrance of cancer cells to blood, increase T cells, inhibits angiogenesis

Hydroxycitrate with garcinia cambogia 750 mg daily

 Action: mimics fasting, enhances chemo, inhibits ACLY fatty acid pathway

Milk thistle 1000mg daily

 Action: liver detox, helps with s.e. of statin/berberine, enhances chemo

Tagamet 200mg daily

 Action- decreases 代謝當量 , increases amount of mebendazole in blood, decreases inflammation, decreases stomach ulcers, helps with Epstein bar virus, and inflammation post-op

22. Niacin 500mg daily

 Action- improves blood circulation

SAM-e 400 mg

 Action: promotes liver health, pub med articles on breast/liver cancer

Boswellia (Frankincese) 1 oil pill daily

Copaiba 120mg daily

 Action: liver health and inflammation

Shark liver oil- 2x a day

 Action: increases WBC’s

Black seed oil 1TBS

 Action: increases T-cells

Maitake-D-fraction 18.3 mg at night &

5 Defenders Immune Strength”- turkey tail, Reishi, Maitake, Shiitake, and chaga sclerotia- 2 daily

 Action: boost immune system, increases natural killer (NK) Cells, MMP-2

Beta Glucan 250mg at night

 Action: helps with immune depleting effects of chemo, increases NK cells

Gymneman Slyvestre 600mg at night

 Action: anti-ox, anti-bacterial, supports healthy blood sugar, increases NK cells, helps with immune depleting effects of chemo

CBD Ultra by Procana- 100mg daily on chemo days

 Helps with nausea and inflammation

Other life supporting therapies:

Infared near sauna

 Action: promote healing to body & detox

Epsom salt/baking soda/essential oil baths

 Action: promote healing, decrease inflammation, and detox

Walks with wife: 2-4 miles most days of the week

 Action: increases oxygenation to tissues, promotes strength & clarity of mind

Anti-inflammatory- low sugar, no grains, no dairy, mostly vegetarian diet (occasional wild caught fish)

Afternoon nap (30-45mins) most days

Berkey filtered water with occasional added ozone- promotes tissue healing in GI tract

Abbreviations/definitions:

 Cancer kill- 2 day span of chemo infusion, IV C infusion with Celebrex/Statin

 Apoptosis- cancer cell destruction

 Angiogenesis- cancer tumor forming and making own blood supply

 Glut 1- glucose transport receptor

 Ox phos- oxidative phosphorylation

 SREBP-1- sterol regulating end binding protein 1

 SREBP-2- sterol regulating end protein binding protein 2

 ACLY- ATP citrate lipase

 F.A.S.- fatty acid synthesis

 F.A.O.- fatty acid oxidation

 mTOR- mammalian Target of Rapamycin

 MMP- matrix metalloproteinases (responsible for 代謝當量 )

 

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